Cossma1607-08_GB

inal the the h a ntar- rod- oba- ated uch tion nter- han ). l re- e to res- iso- tion for ight tem ng a a re- the lost van- aced eria the cha- ergy nex- heir esti- tion ated le. hyl- liso- e or rile ad- er a ver, e is wed the 09), liso- cted and tion ere- rna- This is why we tested a variety of potential pre- servatives and antimicrobial multifunctionals among organic acids, wetting agents and aro- matic alcohols in a series of challenge tests within the original Lactobacillus-contaminated shampoo formulation containing the original alternative preservation system. As a result, out of all the tested substances, only salicylic acid combined with the blend of sodium levuli- nate and sodium anisate led to a significant mi- crobial reduction after seven days (Fig. 2). Based on these results, we came up with an en- hanced preservative blend designed to cope with future microbiological contamination is- sues of our customers. This blend, Verstatil Synacid, is an effective combination of sodium levulinate, sodium anisate and sodium salicy- late at ideal concentrations. It combines the outstanding performance of salicylic acid against resistant germs with the broad antimi- crobial performance of the combination of so- dium levulinate and sodium anisate. In addition, the clear, light yellow liquid of this blend makes handling easier than when using solid pure salicylic acid powder. The blend provedtobehighlyeffectiveinsurfactant-based product concepts, not only against the stand- ard germs from the Ph. Eur. challenge test but also against a variety of well-known prob- lem-causing microorganisms (Fig. 3). In emul- sions, a synergistic combination with a surface active antimicrobial agent, such as Dermosoft GMCY (INCI: Glyceryl Caprylate) is recom- mended and improved the performance even further. □ The reference list as well as additional product information and formula- tions can be found on the Internet – see download panel Fig. 3: Verstatil Synacid in emulsions and surfactant-based formulations tested against well-known problem-causing microorganisms INGREDIENTS www.cossma.com  l  37 a.com Thank goodness the DIN exists in Germany. And even better that DERMATEST® goes that extra mile. We have developed our own quality managment system (certified by TÜV Rheinland) that sets high standards. This system enables us to promise performance that our customers can trust. And the users, too. With standard, three-star and five-star seals of approval DERMATEST®proves the quality we uphold. We offer dermatological clinical application tests and cooperate with other medical specialists such as ophthalmologists, gynecologists, pedia- tricians and dentists.Our tests include simple patch tests conducted in accordance with international guidelines | Measuring skin elasticity (cutometry) | Determining the hydration and fat content of the skin (corneometry, sebumetry) | Sun protection determination according to ISO | Photo patch tests | Long-term (repetitive) patch tests | Safety assessment | Measuring TEWL |Ultrasound examination of the skin | Determining skin roughness using PRIMOS (optical 3-D assessment device) | UVA protection in accordance with ISOstandard | TrichoScan hair analysis | Determining skin properties by confocal laser scan- ning (VivaScope 1500 system) | Human full-thickness skin model for cosmetic testing of efficacy and tolerance. In addition, we can offer you customized test designs to fit your special needs. Dermatest® GmbH Engelstraße 37 48143 Münster T +49(0)251-4816370 www.dermatest.de info@dermatest.de Creativity has many faces Our test designs as well. Developed individually just for you, DIN certified COS1607_34_StraetmansMicrobio.indd 37 26.07.16 16:02 COS1607_34_StraetmansMicrobio.indd 3726.07.1616:02

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