Ī W hile most anti-ageing products promise to fight signs of ageing and turn back time, especially anti-ageing skin care, users over the age of 50 are re- ported to be perfectly comfortable with their age. As they don’t feel old, they are not particularly compelled to look younger, but instead to look the best they can. And that means, above all, to look as healthy as possible. Healthy- looking skin is closely related to the ac- tual main purpose of our skin, which is to function as a physical barrier be- tween our body and the harmful out- side world. Being our skin’s top layer, the epidermis is responsible for main- taining this function. Ageing has a significant impact on the renewal processes in the epider- mis. The proliferation rate of the ker- atinocytes in the basal layer becomes progressively less effective and is re- 10 COSSMA 5I2015 FOCUS: ACTIVE INGREDIENTS PRODUCT DEVELOPMENT ported to be up to 50% slower in peo- ple over 80. The effectiveness of the dif- ferentiation process is reduced as well, which means that the production of key elements in the skin’s barrier func- tion and quality is impaired. Addition- ally, ageing leads to a loss of so-called immunocompetence in the epidermis. Helping the skin to maintain its barrier function To safeguard the skin’s ability to maintain its barrier function, the epi- dermis can, and must, act as a “biosen- sor.” Challenges, such as a fluctuation in environmental humidity or sunlight, etc., can actually be “perceived” by the differentiating keratinocytes, which are able to instantly react and compensate for the negative influence of challenges on the skin’s quality. At the base of this characteristic lies the ability of the dif- ferentiating keratinocytes to react im- munologically. As the skin’s renewal process loses its effectiveness and, as its immunocompetence decreases, aged skin looks less healthy. Therefore supplying modern-day consumers with satisfactory anti-ageing skincare prod- ucts becomes an essential target. To address these needs, CLR has developed ProRenew Complex CLR (INCI name: Lactococcus Ferment Lysate), based on a lysate of Lactococ- cus lactis. This probiotic lactic acid- producing bacterium is grown under specific conditions, after which the ob- tained cells are lyzed – a process in- volving the killing and destruction of the bacterial cells. Probiotic bacteria are well-known for their health-related benefits in the gut. With this active in- gredient, which essentially contains the cell debris of the probiotic bacte- ria, these characteristics were success- fully translated to cosmetic skin care. It has been shown to strengthen the im- mune system of the skin cells and to stimulate the skin’s self-renewal. Probiotics translated into skin care Accelerating skin renewal The beneficial effects of pro- biotic bacteria transferred to cosmetic skin care photos:CLR The new ingredient ProRenew Complex CLR has transferred the ability of probiotics to support the body’s immune system to cosmetic skin care. As the results of in vitro and in vivo studies confirm, it boosts the skin’s renewal processes making them quicker and functioning more effectively. Additional information can be found at www.cossma.com/qr00009 or you can just scan the QR code! Your access codes for May: User name: cossma5 Password: active DownloadsDownloads COS1505_10_CLR_COS1409_10_Van_Hoeven_GB 27.04.15 06:56 Seite 10 COS1505_10_CLR_COS1409_10_Van_Hoeven_GB 27.04.1506:56 Seite 10