Cossma1312_GB_Teaser

Counteracting the force of gravity Tetrapeptide that improves the organisation of functional elastin, by inducing the expression of proteins FBLN5 and LOXL-1, as well as the cellular cohesion, through the upregulation of genes involved in focal adhesions (talin, zyxin, integrins), while enhancing the synthesis of elastin and collagen I. All this is essential to a firm skin. The decrease of the fragmentation rate of the dermis was statistically significant on volunteers with saggy skin after a topical treatment with 2% uplevity™ peptide solution.Placebo cream Cream containing 2% uplevity™ peptide solution 20.0 10.0 0 -10.0 -20.0 -30.0 -40.0 -50.0 -39.6% -37.9% Fragmentation rate for the upper reticulum (%) Fragmentation rate for the deeper reticulum (%) RESTRUCTURATION OF THE DERMIS Lipotec GmbH Nassaustraße 3 65719 Hofheim-Wallau, Germany Tel: +49 (0) 6122538990 Fax: +49 (0) 6933296202 E-mail: info@lipotec.de COS1312_Lipotec_02_215x290mm_1/1_A 25.11.13 13:44 Seite 1

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