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News Fighting cutaneous aggressions ID bio | ID bio has unveiled new studies carried out on its latest active ingredient extracted from buckwheat seeds, Cell’intact (Aqua (and) Polygonum Fagopyrum Seed Extract). An ex vivo evaluation has been realised on reconstructed epidermis to prove its efficiency in the presence of a pollutant (benzo[a]pyrene). The ingredient reduces the proinflammatory answer by acting on interleukin-8 (IL-8), a marker pro- tein that overreacts in case of pollution and leads to cutaneous discom- fort, and it rebuilds and reinforces the architectural epidermis network via the protection of tight junctions’ proteins (Claudins-1 and -4) to avoid premature ageing. The results show that the active ingredient creates a natural shield against pollution and environmental attacks, a preventive and restora- tive action for the protec- tive care of face and body. www.idbio.eu.com New findings prove efficacy DSM | In its latest opinion, the SCCS concluded that alpha-arbutin is safe at levels of up to 2% in face care products and up to 0.5% in body care products. In recent years arbutin has been the subject of safety discussions in the EU. Following the opinion on beta-arbutin, published in 2008 by the SCCS (SCCP/1158/08), the EU Commission called for additional safety data on alpha-arbutin in 2010. DSM submitted an exhaustive product dos- sier to prove the safety of alpha-arbutin. In particu- lar, the evaluation of hydroquinone release, data on alpha-arbutin stabilisation in formulated cosmetic products, and test results explaining the behaviour of alpha-arbutin on the skin were submitted for safety evaluation. DSM introduced alpha-arbutin to the cosmetic industry more than 10 years ago. The activity of alpha-arbutin in promoting the appearance of an even skin tone has been shown in several clini- cal studies. At a 1% concentration level, the molecule outper- formed other commonly used cosmetic ingredients such as kojic acid and beta-arbutin. DSM also shares new research findings confirming extra efficacy on skin by Regu-Scence (see page 10 ff.), a pure white asparagus extract from the Navarra region. The molecule, launched by DSM in 2014, proved to be highly effective in anti-ageing application. Thanks to its mechanism of action, it delays the cellular ageing process by stimulating the skin’s own autophagy capabilities. www.dsm.com Ingredients photo:NadyaKorobkova,Shutterstock.com photo:Madlen,Shutterstock.com Skin tone applications are one of the biggest growing segments in the skin care market Active ingredient extracted from buckwheat seeds PRODUCTION  INGREDIENTS NEWS 42 l COSSMA 9 I 2015 Xh Afj Bei ei könnt 1. Ogd W Auf W Org 2. Sdg W Kom W Einf Bfj Bei ei könnt W Auf juzl W Bra uü+ W Org seit 2004 sellscha Die Solutio auf umse Xhg Bfjh Bei ei könnt schnit W Auf W Bra Xhg Bei ei könnt schnit W Auf W Bra Additional i at www.cos or you can Your acces User name Password: COS_42_44_Ingredients.indd 42 25.08.15 17:25 COS_42_44_Ingredients.indd 4225.08.1517:25

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